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The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4-DRI

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Rosacea isn't just about redness—it's often a sign of a compromised skin barrier and ongoing inflammation. When the barrier is weakened, skin becomes more reactive: • Increased sensitivity • Higher transepidermal water

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Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment

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Rosacea isn't just about redness—it's often a sign of a compromised skin barrier and ongoing inflammation. When the barrier is weakened, skin becomes more reactive: • Increased sensitivity • Higher transepidermal water

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